Title: Direct Determination of Carbohydrates, Amino Acids and Antibiotics by Microchip Electrophoresis with Pulsed Amperometric Detection

Author(s): Henry, Charles S., Carlos D. Garcia

Entity: Colorado State University Research Foundation

Patent Number: WO2005024408 A1. Published: Mar. 17, 2005.

Abstract:
The present invention provides a microchip for performing electrophoresis with pulsed amperometric detection (PAD) for the separation and detection of underivatized carbohydrates, amino acids, sulfur-containing antibiotics, etc. PAD allows for the direct detection of amines, thiols, alcohols and carbohydrates and therefore is a useful technique for the development of electrochemical detection for microchip electrophoresis.