Title: Drug Candidate Screening Systems Based on Micropatterned Hyrogels and Microfluidic Systems

Author(s): Pishko, Michael V., Wong-Gun Koh, Alexander Revzin

Entity: Penn State Research Foundation

Patent Number: US20030175824 A1. Published: Sept. 18, 2003.

Abstract:
A cell-containing, three-dimensional hydrogel microstructure that closely imitate a native cell environment. The three-dimensional hydrogel microstructures may be formed using photolithography either alone or in conjunction with the use of microfluidic networks. The resulting cell- containing, three-dimensional hydrogel microstructures can be used efficiently in various cell monitoring applications, including drug candidate screening systems.