Title: Bioactive Coating of Biomedical Implants

Author(s): Kumar, Sunil, Zhang Hailong

Entity: University Of South Australia

Patent Number: WO 2005/067992 A1. Published: July 28, 2005.

Abstract:
 A method of forming a bioactive coating on a biomedical implant, the method including the step of contacting at least part of the surface of the implant prior to implantation wih a plasma gas containing a reactive hydroxylating oxidant species.  The step of contacting the surface of the implant prior to implantation with a plasma gas containing a reactive hydroxylating oxidant species may be preceded by a step of exposing the implant to an organosilane or organosilicate species to form a silica coating on at least part of the implant prior to contact with the oxidant species.